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Increased Urine Production Due to Leg Fluid Displacement Reduces Hours of Undisturbed Sleep
Author(s) -
KIBA Keisuke,
HIRAYAMA Akihide,
YOSHIKAWA Motokiyo,
YAMAMOTO Yutaka,
TORIMOTO Kazumasa,
SHIMIZU Nobutaka,
TANAKA Nobumichi,
FUJIMOTO Kiyohide,
UEMURA Hirotsugu
Publication year - 2018
Publication title -
luts: lower urinary tract symptoms
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.451
H-Index - 15
eISSN - 1757-5672
pISSN - 1757-5664
DOI - 10.1111/luts.12176
Subject(s) - fluid intake , medicine , urine , nocturnal , risk factor , bedtime , extracellular fluid , displacement (psychology) , chemistry , psychology , extracellular , biochemistry , psychotherapist
Objective To investigate whether or not the leg fluid displacement observed when moving from the standing to recumbent position at bedtime reduces the hours of undisturbed sleep ( HUS ). Methods Men aged 50 years or older who were hospitalized for urological diseases were investigated. Body water evaluation was performed three times with a bioelectric impedance method: (i) 17:00, (ii) 30 min after (short‐term), and (iii) waking up (long‐term). A frequency volume chart was used to evaluate the status of nocturnal urine production, and the factors affecting HUS were investigated. Results A total of 50 patients ( m ean age: 68 years) were enrolled. Short‐term changes in extracellular fluid ( ECF in the legs showed a significant positive correlation with urine production per unit of time at the first nocturnal voiding ( UFN / HUS ) (r = 0.45, P = 0.01). In the comparison between patients who had <3 HUS vs. those who had ≥3 HUS , the <3 HUS group showed significantly greater short‐term changes in leg fluid volume, night‐time water intake (17:00–06:00), and UFN / HUS . Multivariate analysis to assess the risk factors for <3 HUS indicated UFN / HUS as a risk factor in the overall model, and short‐term changes in leg ECF and night‐time water intake as risk factors in the model that only considered factors before sleep. Conclusions Nocturnal leg fluid displacement may increase urine production leading up to first voiding after going to bed, and consequently, induce early awakening after falling asleep.