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Lower Urinary Tract Symptoms are Associated with Erectile Function and Psychological Symptoms in Men with Late‐Onset Hypogonadism Syndrome
Author(s) -
SHIGEHARA Kazuyoshi,
SUGIMOTO Kazuhiro,
KONAKA Hiroyuki,
MAEDA Yuji,
KITAGAWA Yasuhide,
MIZOKAMI Atsushi,
KOH Eitetsu,
NAMIKI Mikio
Publication year - 2014
Publication title -
luts: lower urinary tract symptoms
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.451
H-Index - 15
eISSN - 1757-5672
pISSN - 1757-5664
DOI - 10.1111/luts.12033
Subject(s) - lower urinary tract symptoms , medicine , body mass index , erectile dysfunction , international prostate symptom score , waist , testosterone (patch) , erectile function , urology , population , gastroenterology , gynecology , prostate , environmental health , cancer
Objective We assessed the factors significantly associated with lower urinary tract symptoms ( LUTS ) in men with late‐onset hypogonadism ( LOH ) syndrome. Methods The study population consisted of 258 patients aged 40 years or older diagnosed with LOH syndrome. Each patient completed a questionnaire study, such as the I nternational I ndex of E rectile F unction ( IIEF ) 5, A ging M ale S core ( AMS ), and I nternational P rostate S ymptom S core ( IPSS ). Body mass index ( BMI ), waist size, and muscle volume were measured in all patients, and blood biochemical data, including total cholesterol, triglyceride, hemoglobin A1c, and free testosterone (free T ), were also collected. We analyzed the factors that have effect on IPSS . Results The mean age of the patients was 64.9 ± 8.7 years, and the mean free T value was 7.3 ± 2.2 pg/mL. The critical factors affecting IPSS were IIEF5 score, BMI , muscle volume, age, AMS , and free T ‐value ( P < 0.05). Age showed the strongest significant positive correlation with IPSS (r = 0.321, P < 0.001). Each factor was controlled for age. IIEF5 score and AMS were independent factors affecting IPSS (r = −0.221 and 0.195, respectively, P < 0.05). IPSS showed an inverse correlation with IIEF5 , and a positive correlation with AMS . LUTS also had a weak negative correlation with Free T ‐value but this was not significant (r = −0.121, P = 0.061). Conclusion Lower urinary tract symptoms were significantly correlated with erectile function and psychological symptoms in men with LOH syndrome.