Liver diseases: A major, neglected global public health problem requiring urgent actions and large‐scale screening

CLD s represent an important, and certainly underestimated, global public health problem. CLD s are highly prevalent and silent, related to different, sometimes associated causes. The distribution of the causes of these diseases is slowly changing, and within the next decade, the proportion of virus‐induced CLD s will certainly decrease significantly while the proportion of NASH will increase. There is an urgent need for effective global actions including education, prevention and early diagnosis to manage and treat CLD s, thus preventing cirrhosis‐related morbidity and mortality. Our role is to increase the awareness of the public, healthcare professionals and public health authorities to encourage active policies for early management that will decrease the short‐ and long‐term public health burden of these diseases. Because necroinflammation is the key mechanism in the progression of CLD s, it should be detected early. Thus, large‐scale screening for CLD s is needed. ALT levels are an easy and inexpensive marker of liver necroinflammation and could be the first‐line tool in this process.