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Extrahepatic manifestations of hepatitis E virus
Author(s) -
Kamar Nassim,
Marion Olivier,
Abravanel Florence,
Izopet Jacques,
Dalton Harry R.
Publication year - 2016
Publication title -
liver international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.873
H-Index - 110
eISSN - 1478-3231
pISSN - 1478-3223
DOI - 10.1111/liv.13037
Subject(s) - medicine , membranoproliferative glomerulonephritis , myocarditis , fulminant , immunology , encephalitis , vasculitis , hepatitis e virus , virus , hepatitis , cryoglobulinemia , hepatitis c virus , glomerulonephritis , pathology , virology , disease , kidney , biochemistry , chemistry , genotype , gene
Hepatitis E virus can cause acute, fulminant and chronic hepatitis and has been associated with a range of extrahepatic manifestations. Guillain–Barré syndrome, neuralgic amyotrophy and encephalitis are the main neurological manifestations associated with acute and chronic hepatitis E virus infection. Renal injuries have been also reported, including membranoproliferative glomerulonephritis with or without cryoglobulinemia and membranous glomerulonephritis. Acute pancreatitis, haematological disorders and other autoimmune extrahepatic manifestations of hepatitis E virus, such as myocarditis and thyroiditis, have been also reported. In this comprehensive article, we review all published reports describing hepatitis E virus–associated extrahepatic manifestations.