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Sleep disorders in cirrhotics; How can we detect ?
Author(s) -
Gencdal Genco,
Gunsar Fulya,
Meral Cenk E.,
Salman Esin,
Gürsel Berna,
Oruç Nevin,
Karasu Zeki,
Ersöz Galip,
Akarca Ulus Salih
Publication year - 2014
Publication title -
liver international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.873
H-Index - 110
eISSN - 1478-3231
pISSN - 1478-3223
DOI - 10.1111/liv.12485
Subject(s) - medicine , cirrhosis , hepatic encephalopathy , pittsburgh sleep quality index , liver disease , sleep (system call) , affect (linguistics) , gastroenterology , pediatrics , psychiatry , sleep quality , insomnia , psychology , communication , computer science , operating system
Background & Aims Sleep disorders ( SD s) are common in cirrhotics and are often associated with hepatic encephalopathy. SD s negatively affect patients' daily activities and work efficiency. For this reason, early diagnosis is important. The methods used for diagnosis of SD s are not practical and need longer periods of application and evaluation. In this study, we aimed to investigate sleep disorders and related clinical parameters in cirrhosis and also wanted to investigate the using of Sleep Timing and Sleep Quality Screening questionnaire ( STSQS ), a simple form with a short application time, for diagnosis of SD s and its correlation with Pittsburg Sleep Quality Index ( PSQI ) form. Methods Cirrhotic patients and age‐matched healthy volunteers were enrolled. Patients were excluded from this study if they had neuropsychiatric disease or used excessive alcohol or drugs known to affect sleep. Both groups completed validated Turkish form of PSQI and STSQS . SD was defined as PSQI score (0–21) of >5 or STSQS ≥5. Results One hundred and thirty‐one cirrhotic patients and 18 healthy volunteers were enrolled. SD s in cirrhotics and control group were detected 56.5% and 27.8% by PSQI , 49.6% and 16.7% by STSQS respectively. SD s are the most frequent in the Child C patients, and the least frequent in the Child A patients ( P > 0.05). No correlation was found between the MELD score and SD s. SD s were more common in cirrhotic patients with hypoalbuminaemia and low haemoglobin levels. In addition, the patients with decompensated cirrhosis had more frequently SD s than the patients with compensated cirrhosis. In the patient group, sleep latency and total sleep time, sleep parameters were correlated with SD s. STSQS had statistical significant correlation with PSQI for diagnosis of SD s. Conclusion SD s are common in cirrhotics and STSQS could be an appropriate and practical method for diagnosis of SDS in these patients. We can use it in cirrhotic patients at outpatient clinics.