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Optimal management of HBV infection during pregnancy
Author(s) -
Piratvisuth Teerha
Publication year - 2013
Publication title -
liver international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.873
H-Index - 110
eISSN - 1478-3231
pISSN - 1478-3223
DOI - 10.1111/liv.12060
Subject(s) - pregnancy , medicine , chronic hepatitis , chronic infection , hepatitis b virus , transmission (telecommunications) , immunology , hepatitis b , virology , intensive care medicine , virus , biology , immune system , genetics , electrical engineering , engineering
Chronic hepatitis B virus ( HBV ) infection in pregnancy presents a unique and important challenge. Over 50% of chronic HBV carriers in endemic areas acquire infection vertically from their mothers. More importantly, over 90% of perinatally acquired infections progress to chronic HBV infection. Thus, management of chronic HBV during pregnancy and strategies to prevent mother‐to‐child transmission is an important step in eradicating or reducing the global burden of chronic hepatitis B. In addition, chronic HBV infection in pregnancy presents a unique clinical challenge because of the complex relationship between the physiological changes of pregnancy and the pathophysiological response to HBV . This review will present the current knowledge and a practical approach to management of HBV in pregnancy.