Premium
Proof of concept: could snake venoms be a potential source of bioactive compounds for control of mould growth and mycotoxin production
Author(s) -
VerheeckeVaessen C.,
Monte J.,
GarciaCela E.,
Magan N.,
Medina A.
Publication year - 2020
Publication title -
letters in applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.698
H-Index - 110
eISSN - 1472-765X
pISSN - 0266-8254
DOI - 10.1111/lam.13338
Subject(s) - mycotoxin , biology , aspergillus flavus , food science , fusarium , aflatoxin , aspergillus , penicillium , sterigmatocystin , fungal growth , microbiology and biotechnology , botany
The objective was to screen 10 snake venoms for their efficacy to control growth and mycotoxin production by important mycotoxigenic fungi including Aspergillus flavus , Aspergillus westerdijkiae , Penicillium verrucosum , Fusarium graminearum and F. langsethiae . The Bioscreen C rapid assay system was used. The venoms from the Viperidae snake family delayed growth of some of the test fungi, especially F. graminearum and F. langsethiae and sometimes A. flavus . Some were also able to reduce mycotoxin production. The two most potent crude snake venoms ( Naja nigricollis and N. siamensis; 41 and 43 fractions, respectively) were further fractionated and 83/84 of these fractions were able to reduce mycotoxin production by >90% in two of the mycotoxigenic fungi examined. This study suggests that there may be significant potential for the identification of novel fungistatic/fungicidal bioactive compounds as preservatives of raw and processed food commodities post‐harvest from such snake venoms.