z-logo
open-access-imgOpen Access
Replacing fish meal with cottonseed meal protein hydrolysate affects growth, intestinal function, and growth hormone/insulin‐like growth factor I axis of juvenile blunt snout bream ( Megalobrama amblycephala )
Author(s) -
Yuan XiangYang,
Jiang GuangZhen,
Cheng HuiHui,
Cao XiuFei,
Wang CongCong,
Dai YongJun,
Liu WenBin
Publication year - 2020
Publication title -
journal of the world aquaculture society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.655
H-Index - 60
eISSN - 1749-7345
pISSN - 0893-8849
DOI - 10.1111/jwas.12679
Subject(s) - biology , medicine , cottonseed meal , endocrinology , insulin like growth factor , growth hormone receptor , megalobrama , growth factor , soybean meal , hormone , growth hormone , biochemistry , receptor , raw material , ecology , gene
This study aimed to assess the effects of replacing fish meal with cottonseed meal protein hydrolysate (CPH) on the growth, intestinal function, growth hormone/insulin‐like growth factor I (GH/IGF‐I) axis, and inflammation of blunt snout bream, Megalobrama amblycephala . A total of 300 fish (38.66 ± 0.08 g) were allocated into five groups and fed either the basal diet (CPH 0) or the basal diet that replaced fish meal with 1% (CPH 1), 3% (CPH 3), 5% (CPH 5), and 7% CPH (CPH 7). Dietary CPH 3 increased the activities of protease, Na + /K + ‐ATPase, amylase, creatine kinase, and γ‐glutamyl transpeptidase; microvillus length in the anterior and mid intestines; and the mRNA levels of GH , growth hormone receptor ( GHR ), and IGF‐I without any negative effects on growth. Dietary CPH 7 increased the mRNA levels of tumor necrosis factor‐α, interleukin‐6, IκB kinase alpha, and nuclear factor κB but decreased the transcript level of inhibitor of κB‐α ( p  < .05). Therefore, replacing fish meal with CPH 3 improved intestinal function and the transcription of GH/IGF‐I axis genes without any adverse effect on growth or triggering of inflammation in juvenile blunt snout bream.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here