Open AccessComparison between a flash glucose monitoring system and a portable blood glucose meter for monitoring dogs with diabetes mellitus
Author(s) -
Del Baldo Francesca,
Canton Claudia,
Testa Silvia,
Swales Harry,
Drudi Ignazio,
Golinelli Stefania,
Fracassi Federico
Publication year - 2020
Publication title -
journal of veterinary internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.356
H-Index - 103
eISSN - 1939-1676
pISSN - 0891-6640
DOI - 10.1111/jvim.15930
Subject(s) - medicine , diabetes mellitus , concordance , glucose meter , glycemic , blood glucose monitoring , blood glucose self monitoring , ambulatory , insulin , continuous glucose monitoring , endocrinology
Abstract Background Flash glucose monitoring system (FGMS; FreeStyle Libre) was recently validated for use in diabetic dogs (DD). It is not known if this system is clinically useful in monitoring DD. Objective To compare the clinical utility of FGMS against blood glucose curves (BGCs) obtained with a portable blood glucose meter (PBGM) in monitoring DD. Animals Twenty dogs with diabetes mellitus. Methods Prospective study. Dogs with diabetes mellitus on insulin treatment for at least 1 month were included. Comparisons of insulin dose recommendations based on the in‐hospital GCs acquired using FGMS and a PBGM, consecutive‐day interstitial GCs (IGCs) acquired at home using the FGMS, and consecutive‐day, home vs hospital IGCs acquired using the FGMS were made using concordance analysis. Results There was good concordance between insulin dose recommendations based on FGMS and PBGM generated GCs and IGCs obtained in the 2 different environments on 2 consecutive days, but almost absent concordance between IGCs obtained on 2 consecutive days at home. Glucose nadirs were detected in 34/43 (79%) of Ambulatory Glucose Profile (AGP) reports of the FGMS. In comparison, concordant glucose nadirs were identified in 14/34 (41%) BGCs using PBGM. The individual FGMS scans and PBGM identified 60% and 9% of low IG/hypoglycemic episodes, respectively. Conclusions and Clinical Importance Insulin dose adjustments based on BGCs can be suboptimal. The FGMS allows a more accurate identification of the glucose nadirs and hypoglycemic episodes compared to the use of a PBGM and assessment of day‐to‐day variations in glycemic control.