Open AccessComputed Tomographic Angiography of the Pancreas in Cats with Chronic Diabetes Mellitus Compared to Normal Cats
Author(s) -
Secrest S.,
Sharma A.,
Bugbee A.
Publication year - 2018
Publication title -
journal of veterinary internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.356
H-Index - 103
eISSN - 1939-1676
pISSN - 0891-6640
DOI - 10.1111/jvim.14899
Subject(s) - cats , medicine , pancreas , diabetes mellitus , angiography , pancreatic disease , radiology , gastroenterology , computed tomographic angiography , endocrine system , type 2 diabetes mellitus , cardiology , endocrinology , hormone
Background Diabetes mellitus ( DM ) is a common endocrinopathy in cats. No known diagnostic test or patient characteristic at the time of diagnosis can predict likely disease course, unlike in people in whom computed tomographic angiography ( CTA ) is used. No published data exist regarding the CTA appearance of the pancreas in cats with DM , and thus, it is unknown what if any CTA variables should be further assessed for associations with pancreatic endocrine function. Hypothesis/Objectives A significant difference in pancreatic attenuation, volume, and size will be identified between normal cats and those with chronic DM on CTA . Animals Ten healthy control cats and 15 cats with naturally occurring DM present for >12 months. Methods Prospective cross‐sectional study comparing pancreatic attenuation, enhancement pattern, size, volume, pancreatic volume‐to‐body weight ratio (V: BW ), pancreatic arterial: portal phase ratio (A:P), time‐to‐arterial enhancement, and time‐to‐peak portal enhancement on CTA between sedated healthy control cats and those with chronic DM . Results The pancreas in cats with chronic DM was significantly larger, had higher volume, higher V: BW , and shorter time‐to‐peak portal enhancement on CTA when compared to normal cats. Conclusions and Clinical Importance Peak portal enhancement time, pancreatic size, pancreatic volume, and V: BW can be used to differentiate normal sedated cats from those with chronic DM by CTA . These variables warrant further investigation to identify possible associations with endocrine function.