English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Open

Background  Hyperkalemia is a frequently observed electrolyte imbalance in dehydrated neonatal diarrheic calves that can result in skeletal muscle weakness and life‐threatening cardiac conduction abnormalities and arrhythmias.    Hypothesis  Intravenous administration of a small‐volume hypertonic NaHCO 3  solution is clinically more effective in decreasing the plasma potassium concentration ( c K) in hyperkalemic diarrheic calves than hypertonic NaCl or glucose solutions.    Animals  Twenty‐two neonatal diarrheic calves with  c K >5.8 mmol/L.    Methods  Prospective randomized clinical trial. Calves randomly received either 8.4% NaHCO 3  (6.4 mL/kg BW; n = 7), 7.5% NaCl (5 mL/kg BW; n = 8), or 46.2% glucose (5 mL/kg BW; n = 7) IV over 5 minutes and were subsequently allowed to suckle 2 L of an electrolyte solution. Infusions with NaHCO 3  and NaCl provided an identical sodium load of 6.4 mmol/kg BW.    Results  Hypertonic NaHCO 3  infusions produced an immediate and sustained decrease in plasma  c K. Hypertonic glucose infusions resulted in marked hyperglycemia and hyperinsulinemia, but  c K remained unchanged for 20 minutes. Between 30 and 120 minutes after initiation of treatment, the most marked decrements in  c K from baseline occurred in group NaHCO 3 , which were significantly ( P  < .05) larger during this period of time than in calves in group NaCl, but not group glucose. After 120 minutes, the mean decrease in  c K from baseline was −26 ± 10%, −9 ± 8%, and −22 ± 6% in groups NaHCO 3 , NaCl, and glucose, respectively.    Conclusions/Clinical Importance  Small‐volume hypertonic NaHCO 3  infusions appear to have clinical advantages for the rapid resuscitation of hyperkalemic diarrheic calves, compared to hypertonic NaCl or glucose solutions.

journal of veterinary internal medicine

Effect of Intravenous Small‐Volume Hypertonic Sodium Bicarbonate, Sodium Chloride, and Glucose Solutions in Decreasing Plasma Potassium Concentration in Hyperkalemic Neonatal Calves with Diarrhea