English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Open

Background  Band cells and toxic neutrophils are thought to indicate acute and severe systemic illness but no studies have investigated their importance in adult equine emergency admissions.    Objectives  The objective of this study was to evaluate the association of band cells and toxic neutrophils with systemic inflammatory response syndrome ( SIRS ) and outcome in horses.    Animals  One hundred and five adult horses admitted on emergency basis to a private primary referral practice.    Methods  Prospective observational study with sample collection. All horses admitted on emergency basis over the study period were included in the study if they had a  CBC  and a blood smear collected on admission.    Results  The detection of band neutrophils on admission was associated with the  SIRS  status of the horse ( RR  = 2.80; 95%  CI  = 1.57–4.99;  P  < .001) and with poor outcome ( RR  = 1.88; 95%  CI : 1.05–3.37;  P  = .038). Similarly, the presence of a neutrophil toxic grade higher than 3 was associated with  SIRS  ( RR  = 1.71; 95%  CI : 1.03–2.82;  P  = .034) and death ( RR  = 2.34; 95%  CI : 1.22–4.50,  P  = .007). The information gained from the blood smear review could not be captured by looking at only the  WBC  or neutrophil count.    Conclusions and Clinical Importance  The microscopic review of blood smears from critically ill horses to detect band cells or neutrophil toxic change is valuable and could help in assessing disease severity and prognosis in adult equine emergency admissions.

Association of Presence of Band Cells and Toxic Neutrophils with Systemic Inflammatory Response Syndrome and Outcome in Horses with Acute Disease