Open AccessLetter to the Editor
Author(s) -
Schwartz Denise S.
Publication year - 2015
Publication title -
journal of veterinary internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.356
H-Index - 103
eISSN - 1939-1676
pISSN - 0891-6640
DOI - 10.1111/jvim.13583
Subject(s) - amiodarone , medicine , cats , drug , adverse effect , intensive care medicine , pharmacology , atrial fibrillation
In the article “Cardiopulmonary Resuscitation in Small Animal Medicine: An Update” published in January/February 2008 issue, pages 9–25, there is a table that indicates the use of amiodarone in cats, at the same dose as used in dogs, but I could not find any published study that has tested amiodarone in cats, other than acute experimental studies and in vitro studies, not related to specific feline diseases, but as animal models for human diseases. I believe it is dangerous to recommend clinical use of a drug that has not been tested in this species. Considering the unique characteristics of cats with regard to drug metabolism and amiodarone toxicity in other species, I believe that use in this species could lead to potentially serious or life-threatening adverse effects. Amiodarone use should be carefully evaluated in cats before general recommendation are made. Can the authors provide any information regarding the safety of amiodarone in cats? I would appreciate knowing the basis for recommending the use of this drug in cats. From the article: Reference