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Background  Failure of transfer of passive immunity ( FTPI ) is the underlying predisposing risk factor for most early losses in dairy calves. Refractometers, either optical or digital, can be used to assess  FTPI  as a part of calf health monitoring program on dairy operations.    Objectives  To evaluate the performance of and differences between digital  B rix and optical refractometers for assessing  FTPI  in dairy calves.    Animals  Two hundred  H olstein calves from 1 to 11 days of age.    Methods  A cross‐sectional study was designed to measure serum  I g G  concentration by radial immunodiffusion ( RID ) assay, digital Brix and optical refractometers. The correlation coefficients ( r ) between the 2 refractometers were plotted against each other and against the measured  I g G  concentration from  RID . The  S e,  S p, and accuracy of digital  B rix and optical refractometers for assessing  FTPI  using previously recommended cut‐offs were calculated. A receiver operating characteristic curve was created and used to identify the optimal cut‐off for this dataset.    Results  The  RID I g G  concentration was positively correlated with digital  B rix ( r  =   0.79) and optical ( r  =   0.74) refractometers. The best combination of  S e (85.5%),  S p (82.8%), and accuracy (83.5%) of digital  B rix refractometer was at 8.3% B rix. For optical refractometer, the best combination of  S e (80%),  S p (80.7%), and accuracy (80.5%) was at 5.5 g/dL.    Conclusions and Clinical Importance  Both refractometers exhibited utility in assessing  FTPI  in dairy calves.

Evaluation of Digital and Optical Refractometers for Assessing Failure of Transfer of Passive Immunity in Dairy Calves