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Use of direct oral anticoagulants in patients with thrombotic antiphospholipid syndrome: Guidance from the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis
Author(s) -
Zuily Stéphane,
Cohen Hannah,
Isenberg David,
Woller Scott C.,
Crowther Mark,
Dufrost Virginie,
Wahl Denis,
Doré Caroline J.,
Cuker Adam,
Carrier Marc,
Pengo Vittorio,
Devreese Katrien M.J.
Publication year - 2020
Publication title -
journal of thrombosis and haemostasis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.947
H-Index - 178
eISSN - 1538-7836
pISSN - 1538-7933
DOI - 10.1111/jth.14935
Subject(s) - medicine , antiphospholipid syndrome , lupus anticoagulant , standardization , thrombosis , intensive care medicine , clarity , agency (philosophy) , international standardization , health professionals , health care , surgery , political science , biochemistry , chemistry , philosophy , epistemology , law
Clarity and guidance is required with regard to the use of direct oral anticoagulants in antiphospholipid syndrome (APS) patients, within the confines of the recent European Medicines Agency recommendations, discrepant recommendations in other international guidelines and the limited evidence base. To address this, the Lupus Anticoagulant/Antiphospholipid Antibodies Scientific and Standardization Committee (SSC) chair and co‐chairs together with SSC Control of Anticoagulation members propose guidance for healthcare professionals to help them manage APS patients. Uncertainty in this field will be addressed. This guidance will also serve as a call and focus for research.