Premium
Additional laboratory tests to improve on the diagnosis of antiphospholipid syndrome
Author(s) -
Pengo Vittorio
Publication year - 2020
Publication title -
journal of thrombosis and haemostasis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.947
H-Index - 178
eISSN - 1538-7836
pISSN - 1538-7933
DOI - 10.1111/jth.14896
Subject(s) - antiphospholipid syndrome , medicine , antibody , immunology , lupus anticoagulant , thrombophilia , thrombosis
Whether additional tests to improve on the diagnosis of antiphospholipid syndrome are useful is a matter of debate. New tests exploring the presence of antiphospholipid antibodies are now available and comprise subgroups of antibodies directed to β2‐glycoprotein I, namely anti‐Domain 1 and anti‐Domain 4/5, and anti‐phosphatidylserine/prothrombin antibodies. The aim of this article is to discuss in a forum with the scientific community on the possible utility of additional test for the diagnosis of antiphospholipid syndrome, especially in incomplete antiphospholipid antibody profiles.