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Measurement and prevalence of circulating ADAMTS 13‐specific immune complexes in autoimmune thrombotic thrombocytopenic purpura
Author(s) -
Lotta L. A.,
Valsecchi C.,
Pontiggia S.,
Mancini I.,
Cannavò A.,
Artoni A.,
Mikovic D.,
Meloni G.,
Peyvandi F.
Publication year - 2014
Publication title -
journal of thrombosis and haemostasis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.947
H-Index - 178
eISSN - 1538-7836
pISSN - 1538-7933
DOI - 10.1111/jth.12494
Subject(s) - adamts13 , thrombotic thrombocytopenic purpura , autoantibody , medicine , immunology , confidence interval , gastroenterology , platelet , antibody
The formation of ADAMTS13-specific circulating immune complexes (CICs) may be a pathophysiologic mechanism in autoimmune thrombotic thrombocytopenic purpura (TTP), but has not been systematically investigated.