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Incidence of venous thromboembolism in different ethnic groups: a regional direct comparison study
Author(s) -
Liao S.,
Woulfe T.,
Hyder S.,
Merriman E.,
Simpson D.,
Chunilal S.
Publication year - 2014
Publication title -
journal of thrombosis and haemostasis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.947
H-Index - 178
eISSN - 1538-7836
pISSN - 1538-7933
DOI - 10.1111/jth.12464
Subject(s) - medicine , pacific islanders , incidence (geometry) , confidence interval , pulmonary embolism , demography , ethnic group , venous thrombosis , venous thromboembolism , population , relative risk , pediatrics , thrombosis , physics , environmental health , sociology , anthropology , optics
Summary Background There are few studies that directly compare the variation in incidence of venous thromboembolism ( VTE ) according to ethnicity. Objective The aim of this study was to compare the rates of VTE , deep venous thrombosis ( DVT ) and pulmonary embolism ( PE ) among different ethnic groups. Method The cases diagnosed with VTE , DVT and PE for a period between M arch 2004 and J une 2009 were identified through the hospital‐based database system. The 2006 N ew Z ealand C ensus data were used to calculate the rate of diagnosis. Results The observed annual incidence of VTE during this period was 81.6 per 100 000 population. The relative risks of VTE when comparing E uropean subjects with M aori, P acific I sland and A sian subjects after age standardization were 1.98 (95% confidence interval [ CI ], 1.63–2.41), 3.22 (95% CI , 2.60–3.99) and 4.02 (95% CI , 3.34–4.84), respectively. Relative risks of DVT after age standardization when comparing E uropean subjects with M aori, P acific I sland and A sian subjects, were 2.14 (95% CI , 1.72–2.66), 3.20 (95% CI , 2.46–4.17) and 4.75 (95% CI , 3.80–5.94), respectively. Indirect age standardization was used for comparison of the diagnosis of PE . The ratio between the calculated expected number of cases and the actual number of cases was 1.32 (95% CI , 0.89–1.75) for M aori subjects, 2.96 (95% CI , 1.89–4.03) for P acific I slanders and 3.89 (95% CI , 3.00–4.78) for A sians. Conclusion Europeans have a significantly higher incidence of VTE compared with M aori, P acific I sland and A sian populations.