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Anthropometrical phenotypes are important when explaining obstructive sleep apnea in female bariatric cohorts
Author(s) -
Gasa Mercè,
LópezPadrós Carla,
Monasterio Carmen,
Salord Neus,
Mayos Mercedes,
Vilarrasa Núria,
FernandezAranda Fernando,
Montserrat Josep M.,
Dorca Jordi
Publication year - 2019
Publication title -
journal of sleep research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.297
H-Index - 117
eISSN - 1365-2869
pISSN - 0962-1105
DOI - 10.1111/jsr.12830
Subject(s) - medicine , body mass index , waist , anthropometry , obstructive sleep apnea , obesity , population , waist–hip ratio , demography , sleep apnea , univariate analysis , physical therapy , pediatrics , multivariate analysis , environmental health , sociology
Central obesity is the main risk factor for obstructive sleep apnea ( OSA ). Whether there exists a central‐obesity anthropometric that better explains apnea–hypopnea index ( AHI ) variability in the general population and in sleep cohorts is unknown, and this is even less explored among increasing grades of obesity. The objective of the study is to investigate whether there is an anthropometric that better explains AHI variability in a sample of morbidly obese women awaiting bariatric surgery ( BS ). A prospective multicentre cross‐sectional study was conducted in consecutive women before BS . Demographic and anthropometric characteristics included age, body mass index ( BMI ), neck circumference ( NC ), waist circumference ( WC ), hip circumference ( HC ) and waist‐to‐hip ratio ( WHR ). OSA was diagnosed by polysomnography. The capacity of anthropometrics to explain AHI variance was investigated using regression linear models. A total of 115 women were evaluated: age, 44 ± 10 years; BMI, 46 ± 5 kg/m 2 ; AHI, 35 ± 26 events/hr. AHI was associated with all anthropometrics except weight, height and HC . The best univariate predictor was WHR, which accounted for 15% of AHI variance. The simplest model (age + BMI ) accounted for 9%, which increased to 20% when applying more complex measurements (age + BMI + NC + WC + HC ). The explanatory capacity did not change significantly when applying a simpler model (age + WHR + NC , 19%). In this female morbidly obese cohort, anthropometrics explained one‐fifth of AHI variability. WHR is the best univariate parameter and models including waist and neck data provide more information than BMI when explaining AHI variability. Thus, even in young women with extreme obesity, OSA seems to be linked to a specific central‐obesity phenotype rather than to a whole‐obesity pattern.