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Night‐shift work is associated with poorer glycaemic control in patients with type 2 diabetes
Author(s) -
Manodpitipong Areesa,
Saetung Sunee,
Nimitphong Hataikarn,
Siwasarad Nantaporn,
Wongphan Thanawat,
Sornsiriwong Chotima,
Luckanajantachote Pranee,
Mangjit Prasitchai,
Keesukphan Prasit,
Crowley Stephanie J.,
Hood Megan M.,
Reutrakul Sirimon
Publication year - 2017
Publication title -
journal of sleep research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.297
H-Index - 117
eISSN - 1365-2869
pISSN - 0962-1105
DOI - 10.1111/jsr.12554
Subject(s) - shift work , type 2 diabetes , medicine , body mass index , chronotype , diabetes mellitus , circadian rhythm , calorie , endocrinology , psychiatry
Summary The circadian system plays a role in regulating metabolism. Night‐shift work, a form of circadian misalignment, is associated with increased type 2 diabetes risk. This study aimed to determine if night‐shift workers with type 2 diabetes experience poorer glycaemic control than non‐shift workers. Patients with type 2 diabetes (104 unemployed, 85 day workers and 60 night‐shift workers) participated. Sleep duration, sleep quality, morningness–eveningness preference, depressive symptoms and dietary intake were assessed using standardized questionnaires. Haemoglobin A1c levels were measured. Night‐shift workers had significantly higher haemoglobin A1c levels compared with others, while there were no differences between day workers and unemployed participants (median 7.86% versus 7.24% versus 7.09%, respectively). Additionally, night‐shift workers were younger, had a higher body mass index, and consumed more daily calories than others. Among night‐shift workers, there were no significant differences in haemoglobin A1c levels between those performing rotating versus non‐rotating shifts ( P = 0.856), or those with clockwise versus counterclockwise shift rotation ( P = 0.833). After adjusting for age, body mass index, insulin use, sleep duration, morningness–eveningness preference and percentage of daily intake from carbohydrates, night‐shift work, compared with day work, was associated with significantly higher haemoglobin A1c ( B = 0.059, P = 0.044), while there were no differences between unemployed participants and day workers ( B = 0.016, P = 0.572). In summary, night‐shift work is associated with poorer glycaemic control in patients with type 2 diabetes.