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Home dim light melatonin onsets with measures of compliance in delayed sleep phase disorder
Author(s) -
Burgess Helen J.,
Park Margaret,
Wyatt James K.,
Fogg Louis F.
Publication year - 2016
Publication title -
journal of sleep research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.297
H-Index - 117
eISSN - 1365-2869
pISSN - 0962-1105
DOI - 10.1111/jsr.12384
Subject(s) - circadian rhythm , melatonin , medicine , saliva , population , sleep (system call) , audiology , psychology , environmental health , computer science , operating system
Summary The dim light melatonin onset ( DLMO ) assists with the diagnosis and treatment of circadian rhythm sleep disorders. Home DLMO s are attractive for cost savings and convenience, but can be confounded by home lighting and sample timing errors. We developed a home saliva collection kit with objective measures of light exposure and sample timing. We report on our first test of the kit in a clinical population. Thirty‐two participants with delayed sleep phase disorder ( DSPD ; 17 women, aged 18–52 years) participated in two back‐to‐back home and laboratory phase assessments. Most participants (66%) received at least one 30‐s epoch of light >50 lux during the home phase assessments, but for only 1.5% of the time. Most participants (56%) collected every saliva sample within 5 min of the scheduled time. Eighty‐three per cent of home DLMO s were not affected by light or sampling errors. The home DLMO s occurred, on average, 10.2 min before the laboratory DLMO s, and were correlated highly with the laboratory DLMO s ( r = 0.93, P < 0.001). These results indicate that home saliva sampling with objective measures of light exposure and sample timing, can assist in identifying accurate home DLMO s.