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Genetic background of lumbosacral transitional vertebrae in German shepherd dogs
Author(s) -
Gluding D.,
Stock K. F.,
Tellhelm B.,
Kramer M.,
Eley N.
Publication year - 2021
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/jsap.13380
Subject(s) - lumbosacral joint , medicine , heritability , trait , lumbar vertebrae , anatomy , evolutionary biology , biology , computer science , programming language , lumbar
Objectives Estimation of genetic parameters of lumbosacral transitional vertebrae based on data derived from radiographic screening of 27,597 German shepherd dogs. Materials and Methods Results of radiographic screening for lumbosacral transitional vertebrae classified according to a published scheme were collected. Obtained data were used for estimating variance components in single and multiple trait linear animal models to obtain heritabilities and additive genetic correlations for different types of lumbosacral transitional vertebrae. Results Estimations indicated a moderate heritability of lumbosacral transitional vertebrae of h 2 = 0.27. Trait definitions reflecting the different types of lumbosacral transitional vertebrae revealed positive additive genetic correlations of r g > 0.5 between those types usually categorised as pathologic. Clinical Significance Results of comprehensive genetic analyses enable the development of breeding measures against lumbosacral transitional vertebrae to reduce their prevalence and support management of potentially correlated diseases in German shepherd dogs.