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Comparison of CPAP and oxygen therapy for treatment of postoperative hypoxaemia in dogs
Author(s) -
Stabile M.,
Lacitignola L.,
Piemontese M. R.,
Di Bella C.,
Acquafredda C.,
Grasso S.,
Crovace A. M.,
Gomez de Segura I. A.,
Staffieri F.
Publication year - 2021
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/jsap.13295
Subject(s) - medicine , continuous positive airway pressure , anesthesia , airway , positive pressure , continuous infusion , oxygen therapy , obstructive sleep apnea
Objective To compare 5 cmH 2 O of continuous positive airway pressure with oxygen therapy in dogs recovering from general anaesthesia with low SpO 2 values. continuous positive airway pressure is more effective than oxygen therapy in restoring normoxaemia (SpO 2 ≥95%). Materials and Methods Prospectively, dogs recovering from anaesthesia, with SpO 2 <95% after extubation (T0), were randomised and treated with continuous positive airway pressure (FiO 2 0.21) or oxygen (O 2 ; FiO 2 0.35‐0.40) therapy. Dogs were monitored with SpO 2 every 15 minutes for 1 hour (T15, T30, T45, T60). Data from normoxaemic dogs (SpO 2 >95%) were used as control (CTR). Results Of the 42 dogs enrolled, 34 completed the study. Eleven dogs were treated with O 2 , 10 with continuous positive airway pressure and 13 were CTR. The SpO 2 values at T0 were similar in the continuous positive airway pressure and O 2 groups and were lower than in the CTR group. At T15, T30, T45 and T60, the SpO 2 values in the continuous positive airway pressure group were higher than at T0; these were similar to those of the CTR group at the same time‐points. In the O 2 group, SpO 2 values were significantly higher at T45 and T60 than at T0; 45.5% of dogs became normoxaemic at T45 and the remaining dogs became normoxaemic at T60. The average time to reach normoxaemia in the O 2 group (53.1±7.3 minutes) was longer than in the continuous positive airway pressure group (15.0±0.0 minutes). Clinical Significance In dogs recovering from general anaesthesia with pulmonary gas exchange impairment, normoxaemia is restored more effectively and rapidly by using continuous positive airway pressure than by oxygen therapy.