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Treatment of intrahepatic congenital portosystemic shunts in dogs: a systematic review
Author(s) -
Tivers M. S.,
Lipscomb V. J.,
Brockman D. J.
Publication year - 2017
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/jsap.12712
Subject(s) - medicine , portosystemic shunt , evidence based medicine , best evidence , surgery , intensive care medicine , portal hypertension , pathology , alternative medicine , cirrhosis
The aim of this study was to establish the evidence base for the treatment of intrahepatic congenital portosystemic shunts in dogs through a systematic review of the pertinent literature. Studies were filtered for evidence to answer the question “Which of the treatment options for intrahepatic CPSS in dogs offers the best short‐ and long‐term outcome?” Studies were assigned a level of evidence based on a system published by the Oxford Centre for Evidence‐Based Medicine. Thirty‐two studies were included in the review. Twenty‐six provided level 4 evidence and six provided level 5 evidence. There were no level 1, 2 or 3 studies. One study compared surgical treatment with medical management and one study compared suture ligation with ameroid constrictor placement. The remaining studies were case series describing the outcome for one treatment method alone. Methods and timings of assessments of short‐ and long‐term outcomes were highly varied, making direct comparisons challenging. The evidence regarding the treatment of intrahepatic congenital portosystemic shunts in dogs is weak, with only two studies directly comparing treatments. There is a lack of evidence regarding short‐ and long‐term outcomes on which to base clinical decisions.