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Implication, clinical and biological impact of vector‐borne haemopathogens in anaemic dogs in France: a prospective study
Author(s) -
Bouzouraa T.,
Cadore J. L.,
Chene J.,
GoyThollot I.,
Ponce F.,
ChalvetMonfray K.,
Rannou B.,
Chabanne L.
Publication year - 2017
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/jsap.12690
Subject(s) - haemolysis , medicine , ehrlichia canis , vector (molecular biology) , babesiosis , babesia , mycoplasma , prospective cohort study , veterinary medicine , serology , virology , immunology , biology , microbiology and biotechnology , biochemistry , antibody , gene , recombinant dna
Objectives To prospectively describe the clinical and biological impact of vector‐borne haemopathogens in anaemic dogs in France and occurrence of haemolysis. Materials and Methods This prospective descriptive cohort study includes 134 client‐owned dogs that were anaemic on admission at the Veterinary Teaching Hospital of VetAgro Sup, Lyon, France. They underwent comprehensive screening with PCR to detect a panel of vector‐borne haemopathogens, SNAP Leishmania and SNAP 4Dx Plus (IDEXX). Results Vector‐borne haemopathogen‐associated anaemia accounted for 17·2% (23/134) of anaemic cases. PCR for Babesia species, Mycoplasma species, Anaplasma platys or Ehrlichia canis and positive serology for Leishmania species, occurred in 11/23, 10/23, 2/23, 1/23 and 1/23 cases, respectively. Two dogs had positive PCR for both Babesia and Mycoplasma species. All dogs infected with Mycoplasma species alone had neoplastic disease. Vector‐borne haemopathogens were the second most common cause of haemolysis (7/23, 30·4%). In the multivariable regression model, males were overrepresented ( OR : 2·82, P=0·03) and haemolysis ( OR : 3·31, P=0·01) was more frequent in dogs with vector‐born haemopathogen‐associated anaemia. Clinical Significance Vector‐borne haemopathogens are a common cause of anaemia in this geographical region.