Premium
Bacterial translocation in critical illness
Author(s) -
Krentz T.,
Allen S.
Publication year - 2017
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/jsap.12626
Subject(s) - medicine , bacterial translocation , chromosomal translocation , critical illness , critically ill , intensive care medicine , pathophysiology , microbiology and biotechnology , genetics , biology , gene
Bacterial translocation involves the passage of intestinal bacteria to extraintestinal sites and has been shown to increase morbidity and mortality in critical illness. This review outlines the pathophysiology of bacterial translocation, host defence mechanisms, and reviews the evidence for the clinical management of critically ill patients in order to minimise the negative outcomes associated with bacterial translocation.