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Gingival crevicular fluid IL‐8: correlation with local IL‐1β levels and patient estrogen status
Author(s) -
Payne J. B.,
Reinhardt R. A.,
Masada M. P.,
DuBois L. M.,
Allison A. C.
Publication year - 1993
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/jre.1993.28.6.451
Subject(s) - estrogen , medicine , correlation , dentistry , mathematics , geometry
Gingival crevicular fluid (GCF) IL‐8 and IL‐1,1β levels were determined by sandwich enzyme‐linked immunosorbent assays. Associations between IL‐8 and IL‐1β GCF levels, and between these cytokines and patient estrogen status were evaluated. IL‐8 and IL‐1β were detected more frequently and in higher amounts/30 s GCF sample in estrogen‐deficient patients than in estrogensufficient patients. IL‐8 and IL‐1β GCF levels were significantly correlated. These lindings suggest that GCF IL‐8 levels are associated with patient estrogen status and local IL‐1β concentrations.