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Effects of dietary lysine levels on the concentrations of selected nutrient metabolites in blood plasma of late‐stage finishing pigs
Author(s) -
Regmi N.,
Wang T.,
Crenshaw M. A.,
Rude B. J.,
Liao S. F.
Publication year - 2018
Publication title -
journal of animal physiology and animal nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.651
H-Index - 56
eISSN - 1439-0396
pISSN - 0931-2439
DOI - 10.1111/jpn.12714
Subject(s) - lysine , albumin , randomized block design , zoology , meal , chemistry , crossbreed , globulin , blood chemistry , blood urea nitrogen , biology , biochemistry , endocrinology , food science , amino acid , creatinine , agronomy
Summary Lysine is the first‐limiting amino acid (AA) in typical swine diets and plays very important roles in promoting growth performance of pigs. This research was conducted to study the effects of dietary lysine on blood plasma concentrations of protein, carbohydrate, and lipid metabolites of pigs. Eighteen crossbred finishing pigs (nine barrows and nine gilts; initial BW 92.3 ± 6.9 kg) were individually penned in an environment controlled barn. Pigs were assigned to three dietary treatments according to a randomized complete block design with gender as block and pig as experimental unit (6 pigs/treatment). Three corn and soybean meal‐based diets were formulated to contain total lysine at 0.43%, 0.71%, and 0.98% (as‐fed basis) for Diets I (lysine deficient), II (lysine adequate), and III (lysine excess) respectively. After 4 weeks on trial, jugular vein blood was collected and plasma was separated. The plasma concentrations of total protein, albumin, urea nitrogen (UN), triglyceride, total cholesterol, and glucose were determined using an ACE Clinical Chemistry System (Alfa Wassermann, Inc., West Caldwell, NJ, USA). Data were analysed using the GLM Procedure with PDIFF (adjust = T) option of SAS. No differences ( p > 0.10) were found between barrows and gilts for any of the metabolites measured. While there were no differences ( p > 0.10) between pigs fed Diets II and III in plasma concentrations of UN, albumin, and total cholesterol, the concentration of albumin in these pigs was higher ( p < .05) than that of pigs fed Diet I, and the concentrations of UN and total cholesterol in these pigs were lower ( p < .05) than that of pigs fed Diet I. There were no differences ( p > 0.10) among the three dietary treatments in plasma concentrations of total protein, triglycerides, and glucose. These findings indicated that the plasma metabolite profile can be affected by changing dietary lysine content only. Thorough understanding how the plasma metabolite profile is alternated by dietary lysine will facilitate nutrient management for more sustainable swine production.