Premium
Influence of medium‐chain triglycerides on consumption and weight gain in rats: a systematic review
Author(s) -
Ferreira L.,
Lisenko K.,
Barros B.,
Zangeronimo M.,
Pereira L.,
Sousa R.
Publication year - 2014
Publication title -
journal of animal physiology and animal nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.651
H-Index - 56
eISSN - 1439-0396
pISSN - 0931-2439
DOI - 10.1111/jpn.12030
Subject(s) - weight gain , body weight , zoology , biology , food science , food consumption , consumption (sociology) , endocrinology , agricultural economics , economics , social science , sociology
Summary The use of medium‐chain triglycerides ( MCT s) has been studied for years in an attempt to elucidate their effects in food intake and body weight in animals. The aim of this study was to determine whether there is evidence that the use of MCT reduces consumption and body weight gain in rats, a species chosen as it has been widely used as an animal model in different surveys. A search of scientific work was performed in N ovember 2011 on two bases: ‘Web of Science’ and ‘ P ubMed’. The terms sample size and homogeneity, randomisation, food consumption and weight gain, body composition, enzyme activity and hormonal activity in rats were used as selection criteria. Thirteen papers were selected after the refinement of the research. Twelve studies measured weight gain and among these, seven detected a decrease in weight gain and five found no differences. Twelve papers also measured food intake and among these, four detected a decrease in consumption, one detected an increase and seven found no differences. Based on established criteria for the ranking of scientific papers, it is concluded that there is strong evidence that MCT s can effectively reduce the consumption and subsequent weight gain of animals. However, in the long term, there may not be differences in results depending on the phenotypic adaptation of animals to a new metabolic condition.