Open AccessSolubility of chiral species as function of the enantiomeric excess
Author(s) -
Coquerel Gerard
Publication year - 2015
Publication title -
journal of pharmacy and pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.745
H-Index - 118
eISSN - 2042-7158
pISSN - 0022-3573
DOI - 10.1111/jphp.12395
Subject(s) - solubility , metastability , enantiomer , solvent , phase diagram , enantiomeric excess , chemistry , phase equilibrium , thermodynamics , phase (matter) , organic chemistry , enantioselective synthesis , physics , catalysis
The solubility of racemizable and nonracemizable chiral species is discussed in terms of: enantiomeric excess, nature of solvent and the solid phases, which are in equilibrium with a saturated solution. Stable and metastable equilibria are contemplated by an extensive used of phase diagrams.