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Localization of Gram Negative Urinary Tract Infection by Immunofluorescence in Infants and Children
Author(s) -
BARNETT G. R.,
ABBOTT G. D.
Publication year - 1978
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/jpc.1978.14.3.143
Subject(s) - medicine , urinary system , reflux , asymptomatic , urine , immunofluorescence , asymptomatic bacteriuria , bacteriuria , nephropathy , gastroenterology , reflux nephropathy , direct fluorescent antibody , antibody , pathology , vesicoureteral reflux , immunology , disease , endocrinology , diabetes mellitus
Barnett, G. R. and Abbott, G. D. (1978). Aust. Paediatr. J ., 14, 143–146. Localization of gram negative urinary tract infection by immunofluorescence in infants and children . Bladder urine samples from 97 gram negative urinary tract infections (U.T.Is) in infants and children were tested for antibody coated bacteria (A.C.B.) by immunofluorescence (I.F.). A.C.B. were detected in 14 of 44 episodes of acute pyelonephritis, one of 20 episodes of probable cystitis and five of 33 episodes of asymptomatic bacteriuria. Bladder washout localization reinforced the conclusion that negative I.F. tests are common in upper U.T.Is in infants and children. An association between A.C.B. and renal scarring was observed. Eight of 17 patients with A.C.B. had reflux nephropathy compared with four of 49 patients without A.C.B. Limitations of the test as a screening procedure for renal scarring were evident, however, after finding nine patients with A.C.B. and no renal scarring as well as four patients with renal scarring and no A.C.B.