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Continuous subcutaneous insulin infusion versus multiple daily injections for type 1 diabetes
Author(s) -
Ross Lindsey J,
Neville Kristen A
Publication year - 2019
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/jpc.14480
Subject(s) - medicine , type 1 diabetes , diabetes mellitus , insulin , quality of life (healthcare) , insulin pump , randomized controlled trial , metabolic control analysis , pediatrics , intensive care medicine , endocrinology , nursing
To review the literature on continuous subcutaneous insulin infusion (CSII) and multiple daily injections (MDI) to help the family of a 13‐year‐old girl with type 1 diabetes mellitus on MDI choose the best insulin delivery method for her to improve her glycaemic control. A literature search was performed to assess available evidence regarding CSII use versus MDI use for glycaemic control. We identified 15 relevant articles and present these, with a detailed analysis of a multicentre randomised controlled trial by Mueller‐Godeffroy et al . Although CSII use demonstrated a reduction in HbA 1c (−0.18 to −0.7%) in some studies compared to MDI, this finding was not consistent across all studies. Mueller‐Godeffroy et al . did not find a statistically significant different in HbA 1c between CSII and MDI patients; however, additional benefits of insulin pump therapy, including improved diabetes‐related quality of life and reduced care giver burden, were reported. Further high‐quality randomised controlled trials and long‐term data are required to assess the benefits of CSII over MDI and the longevity of these methods.