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Amlodipine: The double edged sword
Author(s) -
Rabah Fatma,
ElNaggari Mohamed,
AlNabhani Dana
Publication year - 2017
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/jpc.13517
Subject(s) - amlodipine , medicine , culprit , incidence (geometry) , calcium channel blocker , population , anesthesia , calcium , blood pressure , physics , environmental health , myocardial infarction , optics
Aim Amlodipine, a calcium channel blocker became one of the most popular antihypertensive medications used in the paediatric population. This is mainly due to its long half‐life making it easy to use as a single daily dose. Amlodipine is associated with common side effects like flushing, headache and dizziness. The incidence of amlodipine‐related oedema was noted to be lower in the paediatric population compared to adults. We emphasise the importance of monitoring the development of oedema in patients treated with amlodipine. Methods Hereby, we report four paediatric cases with amlodipine‐related generalised oedema. Conclusion Resolution of the oedema with stoppage of amlodipine confirms its culprit as a cause of the oedema. To our knowledge, this is the largest case series of amlodipine‐related generalised oedema in the paediatric population.