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Neonatal outcomes after prelabour rupture of membranes before 24 weeks' gestation
Author(s) -
McLaughlin Linda M,
Gardener Glenn J
Publication year - 2016
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/jpc.13210
Subject(s) - prom , medicine , gestation , obstetrics , rupture of membranes , pregnancy , premature rupture of membranes , gestational age , retrospective cohort study , pediatrics , surgery , genetics , biology
Aim The aim of this study was to determine neonatal outcomes in pregnancies complicated by prelabour rupture of membranes (PROM) before 24 weeks' gestation. Methods We performed a retrospective review of medical records over a 5‐year period (2007–2011) at Mater Health Services, South Brisbane, Australia. Data relating to the antenatal and perinatal course of pregnancies complicated by PROM before 24 weeks' gestation were collected. Data were also collected on neonatal diagnoses, management and outcomes for all liveborn infants resulting from these pregnancies. Results One hundred and six pregnancies were complicated by PROM before 24 weeks' gestation. Thirty‐three (31%) of these pregnancies resulted in delivery at pre‐viable gestations (<23 weeks). There were 36 (37%) infants who survived to hospital discharge. At discharge, 47% of infants had chronic lung disease, with 81% of this group requiring supplemental oxygen at home. Conclusions Almost one‐third of pregnancies complicated by PROM before 24 weeks resulted in pre‐viable preterm delivery. In pregnancies continuing to a viable gestation, there remained a significant risk of neonatal mortality and morbidity, primarily due to respiratory disease.