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Intravenous immunoglobulin in acute S ydenham's chorea: A systematic review
Author(s) -
Mohammad Shekeeb S,
Nosadini Margherita,
GrattanSmith Padraic,
Dale Russell C
Publication year - 2015
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/jpc.12915
Subject(s) - medicine , chorea , antibody , acute rheumatic fever , immunology , intensive care medicine , pediatrics , rheumatic fever , disease
Sydenham's chorea ( SC ) is a major manifestation seen in 25% of patients with acute rheumatic fever. SC is the prototypic autoimmune neurological disorder, which has a less appreciated associated risk of psychiatric morbidity. We undertook a systematic review to examine whether the use of intravenous immunoglobulin affects clinical recovery and morbidity.