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Nutritional status, adiposity and asthma severity and control in children
Author(s) -
Silveira Denise Halpern,
Zhang Linjie,
Prietsch Silvio OM,
Vecchi Amilcare Angelo,
Susin Lulie Rosane Odeh
Publication year - 2015
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/jpc.12882
Subject(s) - medicine , asthma , body mass index , odds ratio , waist , percentile , obesity , confidence interval , logistic regression , pediatrics , abdominal obesity , statistics , mathematics
Aim To investigate association between nutritional status, adiposity and asthma severity and control in children. Methods We conducted a case control study at two teaching hospitals in B razil. Cases were children (3–12 years) with persistent asthma and age‐matched controls were those with intermittent asthma. Nutritional status was assessed by body mass index ( BMI ). Adiposity was assessed by sum of skinfolds and waist circumference ( WC ). Crude and adjusted odds ratios ( OR s) and 95% confidence intervals (95% CI s) were calculated using conditional logistic regression or multinomial logistic regression as appropriate. Results Two hundred sixty‐eight cases and 126 controls were included. Obesity (>2 BMI z ‐score for age) was significantly associated with persistent asthma (adjusted OR 2.62; 95% CI 1.39–4.95). There was a significant linear relationship between BMI z ‐scores (≤1, >1 to ≤2, >2) and risk of having persistent asthma ( P = 0.003 for linear trend). Children with WC >90th percentile had a higher risk of persistent asthma when compared with those with WC ≤90th percentile (adjusted OR 3.38; 95% CI 1.26–9.06). No significant difference was found in terms of nutritional status and adiposity between children whose asthma was controlled by inhaled corticosteroids and those requiring inhaled corticosteroids plus other medications for asthma control. Conclusions Obesity measured by BMI and increased abdominal adiposity are significantly associated with risk of persistent asthma but not type of controller medications.