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H enoch– S chönlein purpura in children
Author(s) -
Trnka Peter
Publication year - 2013
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/jpc.12403
Subject(s) - henoch schonlein purpura , medicine , purpura (gastropod) , nephritis , vasculitis , immunology , systemic vasculitis , pathogenesis , palpable purpura , nephropathy , disease , dermatology , endocrinology , ecology , biology , diabetes mellitus
H enoch– S chönlein purpura is the most common systemic vasculitis of childhood. In the majority of children, the outcome of H enoch– S chönlein purpura is excellent with spontaneous resolution of symptoms and signs. However, a small subset of patients will develop long‐term sequelae in the form of chronic kidney disease. While the clinical presentation and diagnosis of H enoch– S chönlein purpura is straightforward, treatment of H enoch– S chönlein purpura nephritis and long‐term renal outcomes of more severely affected children are less certain. This review article gives a general overview of H enoch– S chönlein purpura with emphasis on recently published information, including the new classification of childhood vasculitis, insights into pathogenesis of H enoch– S chönlein purpura and a summary of various treatments of established H enoch– S chönlein purpura nephritis.