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Enteroviral myocarditis in neonates
Author(s) -
Schlapbach Luregn J,
Ersch Joerg,
Balmer Christian,
Prêtre René,
Tomaske Maren,
Caduff Rosmarie,
Morwood Jim,
Provenzano Sylvio,
Stocker Christian
Publication year - 2013
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/jpc.12248
Subject(s) - medicine , myocarditis , extracorporeal membrane oxygenation , viral myocarditis , fulminant , enterovirus , cardiogenic shock , sepsis , refractory (planetary science) , inotrope , cardiology , immunology , virus , physics , astrobiology , myocardial infarction
Enteroviruses are a leading cause of viral infections in children. While most enteroviral infections are mild and self‐limiting, severe disease such as a viral sepsis syndrome, myocarditis, hepatitis and meningoencephalitis may occur. We present two cases of neonatal enteroviral myocarditis. Cardiorespiratory failure occurred in both cases, and severe shock refractory to conventional treatment required support with extracorporeal membrane oxygenation ( ECMO ). One child with coxsackievirus B 3 myocarditis failed to recover and died after 3 weeks on ECMO , while one child could be decannulated successfully after 9 days of ECMO and recovered completely subsequently. In conclusion, neonatal myocarditis has a very high mortality, and ECMO should be considered early in neonates with rapid clinical and echocardiographic deterioration despite adequate inotropic support.