z-logo
Premium
Early developmental outcome following surgery for oesophageal atresia
Author(s) -
Walker Karen,
Halliday Robert,
Badawi Nadia,
Stewart Jan,
Holland Andrew JA
Publication year - 2013
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1111/jpc.12206
Subject(s) - medicine , gestational age , pediatrics , birth weight , atresia , gestation , surgery , pregnancy , genetics , biology
Aim To compare the developmental outcome of infants with oesophageal atresia with or without trachea‐oesophageal fistula ( OA / TOF ) who underwent surgery in early infancy with healthy control infants in N ew S outh W ales, A ustralia. Methods Infants diagnosed with OA / TOF requiring surgical intervention were enrolled prospectively between 1 A ugust 2006 and the 31 D ecember 2008. Healthy control infants were enrolled in the same time period. The children underwent a developmental assessment at 1 year of age (corrected) using the B ayley S cales of I nfant and T oddler D evelopment ( V ersion III ). Results Of 34 infants with OA / TOF that were enrolled, 31 had developmental assessments. The majority (75%) were term infants (≥37 weeks gestation) with a mean birth weight of 2717 g. Fourteen infants (44%) had an associated birth defect and one infant with multiple associated anomalies subsequently died. Developmental assessments were also performed on 62 control infants matched for gestational age. Infants with OA / TOF had a mean score significantly lower on the expressive language subscale ( P  < 0.05) compared with the control infants. Conclusions This study found a lower than expected developmental score for infants following surgery for OA / TOF in the expressive language subscale compared with the healthy control infants. These findings support concerns over the potential impact of OA / TOF and its effects on development. Further studies, including continuing developmental review to determine whether these differences persist and their functional importance, should be performed.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here