Rapidly evolving hypopituitarism in a boy with multiple autoimmune disorders | Zendy

Jevalikar Ganesh | Zendy; Wong Sze Choong | Zendy; Zacharin Margaret | Zendy

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Rapidly evolving hypopituitarism in a boy with multiple autoimmune disorders

Author(s) -

Jevalikar Ganesh,

Wong Sze Choong,

Zacharin Margaret

Publication year - 2013

Publication title -

journal of paediatrics and child health

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.631

H-Index - 76

eISSN - 1440-1754

pISSN - 1034-4810

DOI - 10.1111/jpc.12169

Subject(s) - medicine , hypopituitarism , diabetes insipidus , pediatrics , hypophysitis , type 1 diabetes , diabetes mellitus , magnetic resonance imaging , autoimmune diabetes , endocrinology , pituitary gland , hormone , radiology

A 10‐year‐old boy with acute onset cranial diabetes insipidus and multiple autoimmune disorders had evolving panhypopituitarism, thought to be due to autoimmune hypophysitis. Over 18 months, a dramatic clinical course with progressive hypopituitarism and development of type 1 diabetes mellitus was evident. Serial brain imaging showed changes suggestive of germinoma.

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