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Feasibility and effectiveness of pre‐emptive rehabilitation in persons approaching dialysis (PREHAB)
Author(s) -
Willingham Fiona C.,
Speelman Irene,
Hamilton Joanne,
von Fragstein Gillian,
Shaw Susan,
Taal Maarten W.
Publication year - 2019
Publication title -
journal of renal care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.381
H-Index - 27
eISSN - 1755-6686
pISSN - 1755-6678
DOI - 10.1111/jorc.12262
Subject(s) - medicine , dialysis , physical therapy , quality of life (healthcare) , attendance , intervention (counseling) , rehabilitation , anxiety , depression (economics) , end stage renal disease , hemodialysis , nursing , psychiatry , economics , macroeconomics , economic growth
SUMMARY Introduction End‐stage kidney disease (ESKD) is characterised by several complications, leading to reduced functional ability and quality of life during transition to dialysis. This study aimed to establish the feasibility and effectiveness of a patient‐centred programme of exercise, nutritional intervention and multidisciplinary education for persons approaching dialysis. Methods Patients with eGFR <15 ml/min/1.73 m 2 and anticipated to start dialysis within 6–12 months were invited to participate. The 10‐week pre‐dialysis intervention included a weekly 1‐hour gym‐based exercise circuit and an education programme. Feasibility and acceptability were assessed through recruitment and retention rates, adherence to the intervention, and from patient feedback following the intervention. Physical function, nutritional status, and anxiety and depression, were assessed at baseline, after intervention, and as dialysis commenced. Results Thirty patients agreed to participate, with 22 completing the pre‐dialysis intervention. Thirteen (59%) participants achieved 100% attendance at the exercise and education sessions, with only two participants attending less than 8/10 sessions. The intervention also led to improved physical function, demonstrated by significant increase in both incremental shuttle walk distance (330 vs. 385 m, p = 0.006) and quadriceps one repetition maximum (p = 0.007), and a trend towards increased sit‐to‐stand repetitions (20–23, p = 0.11). There was a trend for improved patient perception of activity (Duke Activity Status Index score 31.55 vs. 33.75, p = 0.09). Hand grip strength (29.1 vs. 29.8 kg), body mass index (30.4 vs. 30.5 kg/m 2 ) and nutritional status assessed by subjective global assessment (73% well‐nourished) were maintained. Conclusion This study demonstrated the feasibility and effectiveness of a patient‐centred exercise and education programme in those approaching dialysis. Further research is therefore required to evaluate the impact of this programme on clinical outcomes.