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SELF‐REPORTED MEDICATION ADHERENCE IN PATIENTS WITH END‐STAGE KIDNEY DISEASE UNDERGOING ONLINE‐HAEMODIAFILTRATION
Author(s) -
Amado Leonilde,
Ferreira Nuno,
Miranda Vasco,
Meireles Patricia,
Povera Verónica,
Ferreira Ricardo,
FazendeiroMatos João,
Teixeira Laetitia,
Paúl Constança,
SantosSilva Alice,
Costa Elísio
Publication year - 2015
Publication title -
journal of renal care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.381
H-Index - 27
eISSN - 1755-6686
pISSN - 1755-6678
DOI - 10.1111/jorc.12127
Subject(s) - medicine , blood pressure , dialysis , geriatric depression scale , kidney disease , depression (economics) , medication adherence , end stage kidney disease , disease , physical therapy , diabetes mellitus , depressive symptoms , economics , macroeconomics , endocrinology
SUMMARY Introduction Non‐adherence to therapeutic regimens is a recognised problem in the dialysis population that compromises the opportunity to achieve maximum treatment effect and, therefore, might lead to increased morbidity and mortality. In this study, we aimed to evaluate the prevalence of self‐reported medication non‐adherence in patients with end‐stage kidney disease (ESKD) undergoing online‐haemodiafiltration (OL‐HDF), as well as to evaluate the factors that could affect medication adherence. Patients and methods We evaluated 122 patients with ESKD undergoing OL‐HDF. Patients' reported medication adherence was measured by the Measure Treatment Adherence (MTS) scale. Social support was evaluated by the abbreviated Lubben Social Network Scale (LSNS); depression status by the Geriatric Depression Scale (GDS). Socio‐demographic, co‐morbidity and clinical data were also evaluated. Results Our results showed that 10.7% of patients with ESKD perceived themselves as non‐adherent to medication. When two groups of patients (adherent and non‐adherents) were compared, significantly higher levels of triglycerides, and higher diastolic and systolic blood pressure were found in the non‐adherent group. Significant correlations were found between the MTS score, and diastolic blood pressure, age and GDS score. Multiple regression analysis identified age and the GDS score as independent variables significantly associated with the MTS score. Conclusions Non‐adherence to therapeutic regimens in patients with ESKD is associated with higher levels of triglycerides and higher blood pressure and are, therefore, at a higher cardiovascular risk. Moreover, we found that age and depression status are important variables in non‐adherence to therapeutic regimens.