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Antifungal Efficacy and Physical Properties of Poly(methylmethacrylate) Denture Base Material Reinforced with SiO 2 Nanoparticles
Author(s) -
Alzayyat Sara T.,
Almutiri Ghadah A.,
Aljandan Jawhara K.,
Algarzai Raneem M.,
Khan Soban Q.,
Akhtar Sultan,
Matin Asif,
Gad Mohammed M.
Publication year - 2021
Publication title -
journal of prosthodontics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.902
H-Index - 60
eISSN - 1532-849X
pISSN - 1059-941X
DOI - 10.1111/jopr.13271
Subject(s) - contact angle , materials science , acrylic resin , surface roughness , profilometer , vickers hardness test , composite material , nano , candida albicans , nuclear chemistry , chemistry , microstructure , coating , biology , genetics
Abstract Purpose To evaluate the effect of the addition of low concentration of silicon‐dioxide nanoparticles (nano‐SiO 2 ) to poly(methylmethacrylate) (PMMA) denture base material on Candida albicans adhesion, surface roughness, contact angle, hardness, and translucency. Materials and methods A total of 150 acrylic disks were fabricated from heat‐polymerized acrylic resin and specimens were divided into 3 groups of 50 per test. They were further subdivided into 5 subgroups (n = 10) according to the concentration of nano‐SiO 2 : control (no addition) and four tested groups modified with 0.05, 0.25, 0.5, and 1.0 wt% nano‐SiO 2 of acrylic powder. Slide count and direct culture methods were used to measure C. albicans count (CFU/mL). The surface roughness values ( R a ; μm) were determined using a profilometer. The contact angle ( o ) measurement was performed by a goniometer using the sessile drop method. Vickers hardness was used to analyze surface hardness. Translucency was measured using a spectrophotometer. Data analysis was conducted through analysis of variance and Tukey's post hoc tests (α = 0.05). Results Compared to the control group, direct culture and slide count methods illustrated a significant decrease in C. albicans count ( p ˂ 0.001) with the addition of nano‐SiO 2 , and this decrease was correlated with the concentration of nano‐SiO 2 . The addition of nano‐SiO 2 significantly decreased the contact angle ( p ˂ 0.001), whereas hardness and surface roughness significantly increased ( p ˂ 0.001). The addition of nano‐SiO 2 significantly decreased translucency ( p ˂ 0.001), and this decrease was concentration dependent. Conclusion Addition of low concentration of nano‐SiO 2 decreased C. albicans adhesion to PMMA denture base resin. Also, low additions of nano‐SiO 2 have positive effects on contact angle and hardness, whereas surface roughness and translucency were adversely affected at high concentrations.