Premium
In Vitro Comparison of the Cytotoxicity and Water Sorption of Two Different Denture Base Systems
Author(s) -
Akin Hakan,
Tugut Faik,
Polat Zubeyde Akin
Publication year - 2015
Publication title -
journal of prosthodontics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.902
H-Index - 60
eISSN - 1532-849X
pISSN - 1059-941X
DOI - 10.1111/jopr.12162
Subject(s) - sorption , methacrylate , materials science , cytotoxicity , acrylic resin , composite material , monomer , chemistry , organic chemistry , polymer , adsorption , in vitro , coating , biochemistry
Purpose Denture base resins have the potential to cause cytotoxicity in vivo, and the mechanical properties of resins are affected by water sorption. There is a correlation between residual monomer and water sorption. Thus, the purpose of this study was to evaluate water sorption and cytotoxicity of light‐activated urethane dimethacrylate (UDMA) denture base resin compared to a conventional heat‐activated polymethyl methacrylate (PMMA) resin. Materials and Methods Two denture base resins, heat‐activated PMMA (Meliodent) and light‐activated UDMA (Eclipse), were used in this study. Cytotoxicity (5 × 1 mm 2 ) and water sorption (1 × 1 mm 2 ) specimens were made following the manufacturers’ instructions (n = 10). Cytotoxicity tests of denture base resins were performed according to ISO10993–5:1999, and water sorption was evaluated according to ISO 1567:1997. ANOVA tests were employed for evaluating data (α = 0.05). Results There was no cytotoxic effect in either the PMMA or UDMA group. In addition, contrary to short‐term water storage, a significantly lower water sorption value was shown for UDMA resins compared to PMMA resins in both 3‐ and 6‐month storage periods ( p = 0.043 and p = 0.002, respectively). Conclusion The tested denture base materials adhered to the ISO standards for both cytotoxicity and water sorption. The cytotoxicity of the light‐activated UDMA resin tested was statistically similar to that of the heat‐activated PMMA resin; however, the UDMA resin exhibited decreased water sorption in long‐term water storage.