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Prevalence of oral mucosal disorders during pregnancy: A systematic review and meta‐analysis
Author(s) -
Bett João Victor Silva,
Batistella Elis Ângela,
Melo Gilberto,
Munhoz Etiene de Andrade,
Silva Carolina Amália Barcellos,
Guerra Eliete Neves da Silva,
Porporatti André Luís,
De Luca Canto Graziela
Publication year - 2019
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/jop.12831
Subject(s) - medicine , meta analysis , critical appraisal , checklist , grading (engineering) , cinahl , observational study , systematic review , medline , gynecology , dentistry , obstetrics , pathology , psychological intervention , alternative medicine , psychology , psychiatry , civil engineering , political science , law , engineering , cognitive psychology
Objective To assess the prevalence of oral mucosal disorders during pregnancy. Methods Observational studies were selected by two reviewers in a two‐phase process. Search strategies were applied at CINAHL, LILACS, LIVIVO, PubMed, Scopus, Web of Science, Google Scholar, OpenGrey, and ProQuest. The risk of bias was assessed using the Joanna Briggs Institute's Critical Appraisal Checklist for Studies Reporting Prevalence Data. Synthesis of results was calculated by the software R Statistics version 3.5.1 (The R Foundation, Vienna, Austria). Confidence in cumulative evidence was assessed by using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) criteria. Results Fifteen studies met the eligibility criteria and were selected for qualitative synthesis and meta‐analysis, of which 5935 participants were enrolled. The overall prevalence of oral mucosal disorders was 11.8%. Gingival hyperplasia (17.1%), morsicatio buccarum (10%), oral candidiasis (4.4%), pyogenic granuloma (3%), and benign migratory glossitis (2.8%) were the most prevalent lesions. The overall risk of bias was considered moderate, and the quality of evidence was very low. Conclusion Disorders of the oral mucosa were present in approximately 1 out of 10 pregnant women. Gingival hyperplasia was the most prevalent lesion. Further studies should apply homogeneous methodology to improve the quality of evidence.