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Histological analysis of 41 dentigerous cysts in a paediatric population
Author(s) -
Huang Gwendolyn,
Moore Lynette,
Logan Richard M.,
Gue Sumant
Publication year - 2019
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/jop.12776
Subject(s) - dentigerous cyst , medicine , histopathology , pathology , oral and maxillofacial pathology , epidemiology , population , dentistry , dermatology , cyst , environmental health
Background Dentigerous cysts are usually of developmental nature but may be of inflammatory origin especially in paediatric populations. It is important to understand the histological features of dentigerous cysts to enable accurate diagnosis. The aim of this study is to present epidemiological, clinical features and histopathological features of dentigerous cysts seen in a paediatric tertiary referral hospital. Method The medical, radiographic and histopathology records of the Department of Pathology, Women's and Children's Hospital, Adelaide, Australia, during January 1998 to December 2013 were reviewed for patients with dentigerous cysts. All cases were re‐examined by a specialist oral pathologist, consultant paediatric pathologist and paediatric dentistry registrar. Results Forty‐one cases of dentigerous cysts were found. Patients in the permanent dentition were most frequently affected. Male predilection was observed (male:female 2.42:1 ) . The posterior mandible was the most frequently affected region (63.42%) although maxillary canines were the teeth most commonly associated with dentigerous cysts (29.27%). The majority of cases were incidental findings. Squamous epithelium showing pseudoepitheliomatous hyperplasia (46%) was frequently observed and was significantly present with thicker epithelium ( P < 0.0001) and an acute and chronic inflammatory infiltrate ( P < 0.001). Inflammatory infiltrate was seen in 75.6% of cases. Conclusions The current study provides increased knowledge of the histological features of dentigerous cysts in a large retrospective series of paediatric patients and provides further evidence regarding the frequency of inflammatory dentigerous cysts.