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Incidence of lip malignancies in Germany—data from nine population‐based cancer registries
Author(s) -
Singer Susanne,
Zeissig Sylke Ruth,
Emrich Katharina,
Holleczek Bernd,
Kraywinkel Klaus,
Ressing Meike
Publication year - 2017
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/jop.12559
Subject(s) - medicine , skin cancer , incidence (geometry) , cancer , basal cell carcinoma , melanoma , population , basal cell , dermatology , demography , cancer research , environmental health , physics , sociology , optics
Background The objective of this study was to analyse the incidence of lip malignancies in Germany. Methods Data from population‐based cancer registries covering a population of 39 million inhabitants from 14 federal states were pooled. Lip malignancies were classified according to the International Classification of Diseases ( ICD ‐10). Age‐standardised incidence rates and annual percentage changes in the incidence trends of lip cancer (C00), melanoma of the lip (C43.0), and non‐melanoma skin cancer of the lip (C44.0) were calculated. Results Lip cancer (C00) incidence rate was 0.57/0.15 per 100 000 (men/women) in 2003 and 0.52/0.18 in 2012. In women, the change was statistically significant. Melanoma lip cancer (C43.0) incidence rates both in men and women were 0.02 in 2003 and 0.01 in 2012. Incidence rates of non‐melanoma skin cancer of the lip (C44.0) significantly increased from 1.6 in 2003 to 2.1 in 2012 in men and from 1.5 in 2003 to 2.4 in 2012 in women. In lip cancer (C00), the vast majority (98% in men/93% in women) were squamous cell carcinomas and 2%/7% were basal cell carcinoma. In men, 56% of non‐melanoma skin cancers (C44.0) were squamous cell carcinoma, whereas these were only 27% in women. Conclusions The incidences of non‐melanoma skin cancer of the lip increased over time in Germany in both sexes. Lip cancer incidence increased in women, while it stayed stable in men. Melanoma of the lip did not change in incidence. The distribution of histology in non‐melanoma skin cancer of the lip differed by sex.