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Does cell phone use increase the chances of parotid gland tumor development? A systematic review and meta‐analysis
Author(s) -
Siqueira Elisa Carvalho,
Souza Fabrício Tinoco Alvim,
Gomez Ricardo Santiago,
Gomes Carolina Cavalieri,
Souza Renan Pedra
Publication year - 2017
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/jop.12531
Subject(s) - meta analysis , parotid gland , odds ratio , medicine , confidence interval , phone , epidemiology , publication bias , medline , pathology , oncology , biology , philosophy , linguistics , biochemistry
Background Prior epidemiological studies had examined the association between cell phone use and the development of tumors in the parotid glands. However, there is no consensus about the question of whether cell phone use is associated with increased risk of tumors in the parotid glands. We performed a meta‐analysis to evaluate the existing literature about the mean question and to determine their statistical significance. Methods Primary association studies. Papers that associated cell phone use and parotid gland tumors development were included, with no restrictions regarding publication date, language, and place of publication. Systematic literature search using PubMed, Sci ELO and Embase followed by meta‐analysis. Results and conclusion Initial screening included 37 articles, and three were included in meta‐analysis. Using three independent samples including 5087 subjects from retrospective case–control studies, cell phone use seems to be associated with greater odds (1.28, 95%‐ confidence interval: 1.09–1.51) to develop salivary gland tumor. Results should be read with caution due to the limited number of studies available and their retrospective design.