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Oral complications and dental care in children with acute lymphoblastic leukaemia
Author(s) -
Valéra MarieCécile,
NoirritEsclassan Emmanuelle,
Pasquet Marléne,
Vaysse Fréderic
Publication year - 2015
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/jop.12266
Subject(s) - medicine , mucositis , dentition , acute lymphocytic leukemia , cancer , oral health , complication , pediatrics , chemotherapy , dentistry , leukemia , lymphoblastic leukemia , surgery
Acute leukaemia is the most common type of childhood cancer, the acute lymphoblastic type accounting for the majority of cases. Children affected by leukaemia receive various forms of treatments including chemotherapeutic agents and stem cell transplants. Leukaemia and its treatment can directly or indirectly affect oral health and further dental treatments. The oral complications include mucositis, opportunistic infections, gingival inflammation and bleeding, xerostomia and carious lesions. An additional consideration in children is the impact of the treatments on the developing dentition and on orofacial growth. The aim of this review is to describe the oral complications in children with acute lymphoblastic leukaemia and the methods of prevention and management before, during and after the cancer treatment.