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Lichenoid dysplasia revisited – evidence from a review of Indian archives
Author(s) -
Patil Shankargouda,
Rao Roopa S.,
Sanketh D. S.,
Warnakulasuriya Saman
Publication year - 2015
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/jop.12258
Subject(s) - oral lichen planus , medicine , epithelial dysplasia , dysplasia , dermatology , leukoplakia , oral and maxillofacial pathology , fibrous dysplasia , pathology , dentistry , cancer
Aim and objectives To report on the prevalence of ‘lichenoid dysplasia’ ( LD ) in oral mucosal biopsies previously reported as oral lichen planus ( OLP ), oral lichenoid lesion ( OLL ) and oral epithelial dysplasia ( OED ). Based on this case series, to postulate whether features of dysplasia are present in biopsies with a diagnosis of OLP or OLL and vice versa that warrant a separate diagnostic entity of ‘lichenoid dysplasia’. Material and methods This retrospective, multicentre study was carried out by retrieving archival slides of cases diagnosed with OLP , OLL and OED . Diagnostic criteria for the study were based on published guidelines from seminal papers. A total of 165 cases, 70 OLP and OLL and 95 epithelial dysplasia cases, were re‐examined. The diagnosis of OLP s and OLL s was first reconfirmed according to published diagnostic criteria. They were then verified for microscopic features of epithelial dysplasia. Among cases of leukoplakia diagnosed with epithelial dysplasia, we further verified for the presence of lichenoid features. Results A total of 70 cases of OLP and OLL were microscopically evaluated ( OLP ‐54; OLL ‐16). Epithelial dysplasia was noted in 11 cases ( OLP – 8 of 54; OLL – 3 of 16). Nineteen cases of OLP (19 of 54) were found to bear features of OLL s as per published diagnostic criteria. Among the OED group, 22 of the 95 cases showed lichenoid features. Conclusion The study confirms lichenoid features may be found in OED s and epithelial dysplasia may be found in OLP / OLL . We reconfirm that these microscopic features may coexist. Our findings require further discussion by a panel of experts to redefine the entity known as ‘lichenoid dysplasia’. Future studies should address the concept of lichenoid dysplasia that may assist to resolve any controversies with regard to the malignant potential of OLP .